To ensure protection for those most affected, namely women, children, youth, persons with disabilities, people living with HIV/AIDS, older persons, indigenous peoples, refugees and internally displaced persons and migrants, and the poor, vulnerable and marginalized segments of the population, and to prevent all forms of discrimination, especially in the context of timely, universal, inclusive, equitable and non-discriminatory access to safe, quality, effective and affordable health care and services and medical supplies and equipment, including diagnostics, therapeutics, medicine and vaccines, and to leave no one behind, endeavouring to reach the furthest behind first, founded on the dignity of the human person and reflecting the principles of equality and non-discrimination;